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doi: 10.1186/s13052-020-0782-z

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Additionally, treatment with 10 nM E2, for 7 days, stimulated differentiation to the neuronal lineage, and inhibited differentiation to astrocytes (Zhang et al., 2019)

A single 900 mg dose, which matches the adult tolerable upper limit, measurably increased blood NAD+ levels within hours in healthy adults