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The Wolverine protocol is not appropriate for patients who are pregnant or breastfeeding, have active cancer or a recent cancer history (because BPC-157 promotes angiogenesis, which could theoretically support tumor growth), or are on immunosuppressive therapy

A study published in PLoS ONE found that six 40-second sprints increased plasma BDNF four to five times compared to steady low-intensity cycling

A significant inter-group difference in glycemic levels was noted: participants in the KD group exhibited stable glucose levels (60140 mg/dl), whereas the standard diet group showed post-meal glucose spikes for 2 hours, with baseline levels of 80100 mg/dl rising to 150180 mg/dl during meals

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