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Consequences of Excess Vitamin B12 Vitamin B12 is water-soluble, and excess amounts in the body can be easily excreted through urine, making it less toxic

It also activates pathways like Egr-1, NAB2, and JAK-2

However, increased growth hormone activity may carry risks such as: insulin resistance fluid retention and joint swelling cardiovascular complications abnormal tissue growth Human orthopaedic evidence remains limited, and most musculoskeletal data are still preclinical