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If the expected response to medical therapy does not occur, the diagnosis should be reconsidered

This may result in sense loss, difficulty in proprioception, neuropathic pain, difficulty walking, poor balance, loss of sensation in the feet, muscle weakness, blurred vision (either due to retinopathy [27] or optic neuropathy [28] ), impaired urination, fertility problems, decreased sense of taste and smell, decreased level of consciousness, changes in reflexes, memory loss, mood swings, depression, irritability, cognitive impairment, confusion, anxiety, clumsiness, dementia, and, in more severe cases, psychosis

Read Guide The MHRA, Research Peptides & UK Compliance: What Changed in 2026 A plain-English guide to the UK regulatory picture for research peptides in 2026 what the MHRA's action targeted, what 'research use only' actually means, and what compliant, transparent sourcing looks like

This targeted mechanism minimizes the risk of off-target effects and supports the compounds favorable safety profile