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Global, regional, and national burden of non-rheumatic calcific aortic valve disease from 1990 to 2021, with projections of incidence to 2050: a systematic analysis of the global burden of disease study 2021 and Mendelian randomization analysis Meng Xia, Cheng Qian, Yi Luo, Yu Wang, Yongquan Peng, Chunxiang Zhang Journal of Cardiothoracic Surgery

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