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The glutamate co-release of DA neurons expressing VGLUT2 drives the burst discharge of cholinergic interneurons, stimulates the nicotinic acetylcholine receptor at the end of DA neurons, and promotes DA/glutamate co-release, forming a positive feedback loop [167]

In plain terms, it is interesting because it touches multiple systems the body uses when tissue is under stress

Please note that this information should not be treated as a replacement for physical medical consultation or advice