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a) Overlap of the 16/SjGST cocrystal structure (PDB: 8GYD, with compound 16 depicted in green, SjGST in blue, and key residues shown in a gray sticks) with the IBZGSH/SjGST structure (PDB: 1M9B, where IBZGSH is shown in magenta and SjGST is represented by orange lines)

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