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thus, constituting another limitation in this study

Since senescent cells may release a senescence-associated secretory phenotype, the authors suggest that lowering the senescent cell burden may reduce pro-fibrotic signaling in the surrounding cells

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Enzymes such as superoxide dismuatase (SOD), catalase (CAT) and GPx can decompose ROS and prevent the damage to cellular constituents and initiation of lipid peroxidation