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Highly disordered proteins can be readily recognized by CD, since they lack any significant organized secondary structure and therefore have a peculiar far-UV CD spectrum resembling that of an unordered polypeptide, with a strong negative band near 200 nm and either a weak negative shoulder or a weak positive maximum near 220 nm (Woody, 2010)

Specific neurotrophic effects of HGF were reported on calbindin-D containing hippocampal neurons (Korhonen et al., 2000) and dopaminergic mesencephalic neurons (Hamanoue et al., 1996