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Mechanism 2: Block NADPH (Or Bind To NADPH And Change Its Structure) Theres also research showing that instead of competing with NADPH, Finasteride may instead bind to NADPH and change NADPHs structure into a different coenzyme one that doesnt support the formation of 5-alpha reductase

Hou L, Honaker MT, Shireman LM, Balogh LM, Roberts AG, Ng KC, et al

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