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The genus has a number of interesting leaf surface compounds that might affect interactions with insects and plant pathogens in other crop species

Although several carcinogens were already known at the time (for example, benzo[a]pyrene was isolated from coal tar and demonstrated to be a potent carcinogen in 1933), none were known to be contained in adequate quantities in tobacco smoke

Tobacco smoke contains thousands of dangerous chemicals that enter your lungs and bloodstream that cause your heart to beat faster and increase levels of bad LDL cholesterol, blood pressure, and chances of blood clots which can lead to a stroke

Miyake S, Kim S, Suda W, Oshima K, Nakamura M, Matsuoka T, Chihara N, Tomita A, Sato W, Kim SW, et al