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The authors found evidence of ultrastructural abnormalities in cardiomyocytes, including shrunken nuclei with chromatin condensation and fragmentation (apoptosis), nuclear malformation with extensively convoluted nuclear membranes, myofibrillar derangement, thinning and destruction, intramyocardial lipid accumulation and mitophagy, which are associated with myocardial dysfunction

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Recognizing the harmful impact of tobacco in terms of indoor pollution and on biodiversity turns tobacco from an issue of individual well-being to one of global well-being