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Then, due to the proximity that macrophages and tumor cells reside in, interactions between VCAM-1 and the 4 integrins are promoted, which recruit Ezrin, a cytoplasmic adaptor protein that links the actin cytoskeleton to the cytoplasmic tail of VCAM-1, and ultimately results in tyrosine phosphorylation of Ezrin

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The progress of an interactive contact-response arc that combines relative risk of PM 2.5 effluence from various causes (household air pollution, ambient air pollution, tobacco smoking, and second-hand smoke) into a single curve on which risk levels are calculated addressed the need for credit risk estimates for nations with air pollution concentrations beyond those of the sample populations (85, 86)

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