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Epidermal-FABP (FABP5), an extensively studied member of the FABP family, was has been reported to be positively correlated with adiposity, glucose metabolism, and lipolysis parameters and linked to the development of AD (105, 106)

Interestingly, the levels of glutathione and mitochondrial function, which were lower in older mice before taking GlyNAC, and oxidative stress, which was higher before GlyNAC, also were comparable to those found in younger mice after taking GlyNAC for six weeks

Full Staggered Titration Schedule Recommended staggered co-titration across 24 weeks Phase Tirz initiation Weeks 1-4 Tirzepatide 2.5 mg/week Cagrilintide Not started Notes Confirm tirzepatide GI tolerance first