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PMID: 38926151 J Immunother Cancer Costimulation of TCR and TLR7/8 promotes V2 T-cell antitumor activity by modulating mTOR pathway and APC function

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Furthermore, 2-DG-mediated inhibition of glycolysis effectively reverses various electrophysiological alterations induced by epilepsy, suggesting that targeting lactate metabolism pathways could be a promising approach for the development of novel antiepileptic drugs [195] (Supplemental Table 2)