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Upon activation, autoreactive T lymphocytes differentiate into helper T (Th) cells, which secrete a variety of pro-inflammatory cytokines and chemokines that induce immune activation and inflammation ( T-reg: Regulatory T cells (Tregs) play a crucial role in cancer, autoimmune diseases, chronic inflammation, and infectious diseases by regulating self-tolerance and suppressing immune responses

1994 Dec;8(15):1302-7

Role of HO-1 in regulating diabetic cardiomyopathy Diabetic cardiovascular disease is the microvascular and macrovascular disease of the cardiovascular system caused by diabetes, which includes coronary heart disease, diabetic cardiovascular autonomic neuropathy, and diabetic cardiomyopathy [84]

Abstract Keloids are pathological scars exhibiting tumour-like aggressiveness and high recurrence rate