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1 Introduction Hashimotos thyroiditis(HT) is a common autoimmune disease with a prevalence of 14.19% in China and is 2-3 times more common in women than in men ( The highest concentration of selenium across tissues is found in the thyroid ( Vitamin D plays a significant role in maintaining calcium and phosphorus balance and bone health ( In addition to selenium and Vitamin D supplementation in HT patients, Krysiak et al