These can be counted as influenza, smoking, and alcohol consumption, asthma, chronic obstructive pulmonary disease, chronic heart disease, spleen removal (splenectomy) or inability of the spleen to function adequately due to some blood diseases (hypersplenism), diabetes patients, diseases and medications that cause suppression of the immune system, especially HIV infection
References Arranz L, et al
He also flags that glutathione contains a thiol group that oxidizes in water over time, converting the active form to an inactive one, and recommends using reconstituted vials within 14 days rather than the 28-day window common with other peptides
that is, respective 50%, 31%, and 19% comparisons showed lower, equal, and higher levels in vitiligo samples