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Class-level findings do not guarantee equivalent compound-level outcomes

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Mucolytics For pulmonary diseases in which mucus exhibits elevated viscoelasticity, mucolytics can enhance drug retention and penetration 11

Single-dose oral administration of EXEL-2880 resulted in prolonged inhibition of phosphorylation of constitutively phosphorylated Met in B16F10 solid tumors as well as ligand HGF-stimulated phosphorylation of Met in whole liver [78]