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However, CagriBB has equivalent potency to Cagri, in CRE-reporter assays in mammalian cells expressing AMY 3 Rs (Supplementary Table 4), suggesting there is negligible impact of this rotamer difference

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Shrestha S, Yang K, Wei J, Karmaus PW, Neale G, Chi H

Putative role of neuronal 5-lipoxygenase in an aging brain