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In early studies, patients lost 15% or more of their body fat within one year, and almost half the trial participants lost 20% of their body weight

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This was followed by active clinical development for the treatment of several autoimmune diseases, and the first indication for which efgartigimod entered late-stage clinical trials was gMG, which was found to be ameliorated by intravenous (i.v.) delivery of efgartigimod in a pivotal, proof-of-concept, phase II study in 2019 [227]

Tirzepatide is a GLP-1 agonist, meaning it works the same way as liraglutide and semaglutide by controlling hunger levels and cravings