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We then calculated the linearity of the association between the amount of change in smoking and the incidence of lung cancer by testing whether the coefficients associated with the nonlinear components were equal to zero

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The fact that smoking likely led to the deaths of numerous male models featured in the ads along with John Wayne, the poster boy of the American movie fascination with the cowboy seemed to not bother the company at all

2006), showing that much of the decline in youth prevalence rates in this century has simply offset the significant increase in youth smoking that had occurred in the 1990s