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Similarly, metallic nanoparticles (MNPs) (gold, silver, zinc oxide) are conjugated with phytoextracts like Aloe barbadensis , Leucas aspera , Pyrenacantha grandiflora , and Withania somnifera for wide therapeutic efficacy against microbial infections, ulcerative colitis, cancer, and oxidative stress by facilitating extended drug circulation, intercellular targeting, drug stabilization, and higher delivery [19, 20]