cagrilintide and tirzepatide together Beyond semaglutide tirzepatide, where might we find the next GLP-1-based advances in #weightloss #obesity Take a look at the slope of the lines for the combination of + semaglutide and Tirzepatide Bac Water Calculator: Mixing

The serine hydrolase ABHD6 is a critical regulator of the metabolic syndrome

What stood out: CagriSema achieved 23.0% weight loss at 84 weeks (efficacy estimand) Tirzepatide achieved 25.5% On the treatment-regimen estimand, weight loss was 20.2% vs 23.6% Primary endpoint not met: CagriSema did not demonstrate non-inferiority vs tirzepatide on weight loss at 84 weeks Why this matters This is a reminder that in obesity pharmacotherapy, very effective and best-in-class are not the same conversation

Then, she repeated this evaluation after 1 month, and again after 6 months

Dominik Malekinusic, Departments of Pharmacology and Pathology, Medical Faculty University of Zagreb, Zagreb 10000, Croatia