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Serine is an essential metabolite for effector T cell expansion

The common clinical goal of statins is to reduce LDL-C, but statins have various effects on many other biochemical pathways, and those effects may be commonsensical expected to differ from statins to statins ( Overwhelming accumulation of Fe 2+ , ROS and lipid peroxidation occurs in atorvastatin treatment cells in our study

However, under oxidative stress conditions, Nrf2 dissociates from Keap1 and translocates to the nucleus, where it activates various antioxidant genes, including HO-1, protecting cells from oxidative damage

Ho, T.-T., Murthy, H