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Aggressive Angiomyxoma Clinical Aggressive angiomyxoma is synonymously referred to as deep angiomyxoma It is a locally infiltrative tumor of the deep soft tissue of the pelvicperineal region AA mainly occurs in women in the third to fourth decades Typical presentation is a large, often greater than 10 cm in size, slow-growing, and painless mass that is often thought to be Bartholin gland cyst clinically The masses are often substantially larger on image studies than clinically suspected Symptoms are usually vague and may have slightly increased pressure in the urogenital or anorectal areas