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Those who should avoid taking naltrexone have conditions like current opioid use, liver disease, pregnancy and breastfeeding, severe kidney disease, active alcohol use in an extended-release form, severe depression, or suicidal thoughts

Centers for Disease Control and Prevention, THC can be passed to infants and children through secondhand smoke, and people exposed to secondhand marijuana smoke can experience psychoactive effects. More recent research published supports the evidence reported in the earlier scientific statements: A new study presented at the American Heart Associations Epidemiology and Lifestyle 2023 meeting found that vaping THC was associated with self-reported symptoms of depression and anxiety, even more so than vaping nicotine

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