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Whilst competition with other microorganisms for nutrients is intense, an ability to assimilate alternative carbon and nitrogen sources, and to enable directional growth with filament development, is no doubt an advantageous survival strategy

The two core mechanism papers were retracted in April 2025 (Kawas 2012, PMID 22129598, retraction notice PMID 40312092

doi: 10.1158/0008-5472.CAN-05-1162

FOXO4-DRI represents one of the most promising tools of modern senotherapy a new therapeutic approach that focuses not just on alleviating the symptoms of aging, but on the deep-seated cellular mechanisms that drive it