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In: Malins DC, Ostrander GK (eds) Aquatic toxicology: molecular biochemical and cellular perspectives

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"We believe maintaining the glutathione-to-iron ratio is very important, because if you have too little glutathione, then iron becomes very reactive, and if you have too much glutathione, the iron will not be usable." Their experiments determined that SLC25A39 carries a unique iron signature on its surface as part of the glutathione sensing mechanism

Keywords: glucose-6-phosphate dehydrogenase, X-ray crystallography, electron cryo-microscopy, fused glucose-6-phosphate dehydrogenase6-phosphogluconolactonase, F 420 -dependent glucose-6-phosphate dehydrogenase, human and trypanosomatid species Abstract Glucose-6-phosphate dehydrogenase (G6PD) is the first enzyme in the pentose phosphate pathway