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doi:10.1016/S0140-6736(23)01053-X PubMed: This trial evaluated retatrutide in 281 participants with type 2 diabetes, showing up to 16.94% weight loss and significant HbA1c reductions with favorable safety profile comparable to other GLP-1 based therapies

Peptide therapy uses targeted amino-acid sequences that mimic or influence natural hormones and growth factors in the body, delivered most often by subcutaneous injections, occasionally by oral or other routes depending on the molecule

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Safety Considerations and Adverse Event Profiles The safety ratings of both peptides are usually good, with stomach problems being the most common side effect