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ERAD helps mitigate this burden by degrading these proteins, thereby preventing their aggregation and the subsequent activation of detrimental pathways, such as chronic ER stress, autophagy dysfunction, and apoptotic signaling

J Plant Physiol 162:291299 nyayar S, Kele Y, eki F (2005) The antioxidative response of two tomato species with different drought tolerances as a result of drought and cadmium stress combinations

Long-term human safety data simply does not exist in published form

These insights are significant for the design of GO-based antimicrobial agents, as they highlight the importance of tuning nanosheet size to maximize bactericidal activity while minimizing potential toxicity to mammalian cells