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In accordance with this, TGF- in the TME of MCA-induced fibrosarcoma promoted NK cell conversion into a more immature and less cytotoxic phenotype, defined as ILC1-like, characterized by a pro-angiogenic signature (114)

Macerate in a Waring blender (or other rotating blades device) at full speed for a total time of 3-5 min at 4C, using 1 min bursts and 1 min rests to dissipate any heat (see Note 1)

Its well-characterized mechanisms of action, favorable safety profile, and consistent biological effects make it an invaluable compound for researchers exploring wound healing, skin biology, hair follicle cycling, inflammatory resolution, and age-related tissue changes