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As we explained in the FY 2023 IPPS/LTCH PPS final rule (87 FR 49042), we believe applying the scaling factor is appropriate for purposes of calculating Factor 3 for all hospitals, including new hospitals and hospitals that are treated as new hospitals, in order to improve consistency and predictability across all hospitals

Pro-Oxidant Function of Selenium In humans, according to World Health Organization (WHO) standards, the recommended dose of Se for adults is 55 g/day, while the maximum tolerable adult intake without side effects is set at 400 g/day [273]

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