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The gut microbiota produces metabolites, such as serotonin, that influence neuronal function, while the brain sends signals, including dopamine, that can directly or indirectly impact the gut microbiota [16]

Possible reactions noted in the available literature include injection-site irritation, mild headache or fatigue, transient changes in dream vividness or sleep timing, and, occasionally, mild mood shifts or increased restlessness

Monday-Wednesday-Friday dosing creates relatively stable peptide presence

We selected the most abundant clones from the respective libraries, aML5, aMD4 and aMD5 (named after the anti-Met L- or D-number of the cloned peptide), for further characterization (Supplementary Table 2)