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Herxheimer reactions , also simply referred to as Herx reactions, are temporary exacerbations of symptoms that can occur shortly after starting a treatment for certain infections

Presenilin 1 familial Alzheimers disease mutation leads to defective associative learning and impaired adult neurogenesis

Renin-angiotensin system inhibition ameliorates CCl4-induced liver fibrosis in mice through the inactivation of nuclear transcription factor kappa B

A reduction of the N-terminal peptide bond of 25 , with the ambition to achieve a compound even more resistant to proteolytic cleavage, provided 26 ( 26 displays a Ki value in the micromolar range in sharp contrast to what could be expected considering the results obtained after reduction of Ang IV or Nle-Ang IV, cf