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Methods Strains, plasmids and molecular biology methods All the strains and plasmids used in this study are listed in Table 1

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Other Ingredients: purified water, vegetable glycerin, sunflower lecithin with tocopherols, natural flavors, organic acacia gum, potassium sorbate, Lipid-Protect [oleic acid, CoQ10, tocotrienols with carotenoids, cetyl myristoleate (from Kombo nut oil)(Pycanthus angolensis), astaxanthin (from Haematococcus pluvialis algae oil)]

Fractions containing SF3B1 were pooled together, washed with PBS and concentrated in an Amicon Ultra-4 Centrifugal Filter Unit (Sigma-Aldrich, UFC801024)