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Moreover, based on the accumulating evidence that associates mitochondrial abnormalities and elevated ROS levels with multiple neurodevelopmental disorders such as autism [31,32,33,34], schizophrenia [35], Rett syndrome [36], Down syndrome [37], and others [20, 38], it is possible that the herein findings carry significance to the early development of these neurodevelopmental disorders as well, and that mitochondrial anomalies and elevated ROS levels during embryonic development are part of their etiology

This follow-up is especially important for individuals with recurrent infections or underlying health conditions that may predispose them to further issues

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Progress in Retinal and Eye Research , 81 , 100880