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For first-time users, the published evidence base is strongest on topical at 1 to 2%

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Your protocol What to Expect: Smoother texture and improved glow within 2 to 4 weeks Fine lines softening and pores appearing smaller within 4 to 8 weeks Firmer skin and improved elasticity over 8 to 12 weeks Continued collagen remodeling with consistent use Includes: 30gm cream with GHK-Cu + Tretinoin + Estriol + Niacinamide One month supply with nightly application protocol Provider guidance on usage and tolerance building Free shipping Most patients start every other night and increase to nightly use as skin adjusts