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167,168,169 Unlike other nucleic acid-based drugs, aptamers specifically recognize and bind target molecules, such as peptides, proteins, viruses, bacteria, and cells, relying on their unique three-dimensional conformation

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Osteoblasts mediate insulin-like growth factor-I and -II stimulation of osteoclast formation and function

4.1.2 Natural products and small molecule agonists Numerous recent literature reports that various natural products and synthetic small molecules can effectively inhibit chondrocyte ferroptosis by activating the SLC7A11/GPX4 axis or the Nrf2GPX4 signaling pathway