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H.StahlE.ErdmanR.GatalicaZ.et al (2015)

Phase Initial 4 weeks Daily Dose 300 mcg Volume 0.18 mL Units (U-100) 18 units Phase Maintenance (weeks 5-12) Daily Dose 500 mcg Volume 0.30 mL Units (U-100) 30 units Phase Optional extension Daily Dose 300-500 mcg Volume 0.18-0.30 mL Units (U-100) 18-30 units This summarizes the published research-context dose range (commonly cited 300-500 mcg/day)

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Photolytically released nitric oxide produces a delayed but persistent suppression of LTP in area CA1 of the rat hippocampal slice