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studied the combination of L-carnitine, branched-chain amino acids, and exercise on 11 patients with cirrhotic cramps

Current Opinion in Clinical Nutrition and Metabolic Care, 7 (4), 405-410

Some research suggests they might affect prostaglandin synthesis, which could potentially influence smooth muscle contraction in the intestinal wall and alter gut transit time, though this effect is generally modest at recommended doses and the evidence is not conclusive

Further research should be performed on personalized Se supplementation approaches using genetics and nanotechnology to optimize the bioavailability and efficacy of the supplements