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Red blood cells carry oxygen to the brain and other organs, causing a lack of energy and depression without them

[DOI: 10.1136/bmj.c365] [DOI] [PubMed] [Google Scholar] Lam 2013 Lam JR, Schneider JL, Zhao W, Corley DA

The purpose of this replacement therapy is to replace substances that aren't working properly in your body with ones that are more effective

22,23 In patients with a normal or low-normal serum vitamin B 12 level, complete blood count results demonstrating macrocytosis, or suspected clinical manifestations, a serum methylmalonic acid level is an appropriate next step 1,2,6,18 and is a more direct measure of vitamin B 12 's physiologic activity