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Concomitant administration of glutathione precursor N-acetylcysteine (NAC) has been shown to reduce cisplatin-induced nephrotoxicity and as a standard treatment for paracetamol overdose by replenishing depleted GSH

[Abstract]2020 Jan;18(1):57-69

Tobe R, Mihara H

Hence, instead of positively transmitting a Ca2+ signal, some types of protein phosphatase such as PP2C act as a negative regulator of ABA signaling (Leung et al., 1994