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Guideline 1: Tailoring B12 Therapy to Underlying Causes Effective B12 therapy needs a personalized touch

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Navitoclax (ABT-263), another inhibitor of the BCL-2 family members, has also been used in many different studies over the years for its ability to eliminate senescent cells by inducing apoptosis

19,20 With aging, mitochondrial function declines, leading to decreased energy metabolism, increased ROS production, and the accumulation of mtDNA mutations, alongside the deterioration of other mitochondrial functions