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By promoting cellular repair and improving microcirculation, PDA may help reduce postoperative pain, speed healing, and enhance overall recovery outcomes without interfering with standard surgical protocols

One should consider the primary phase lesion and hemorrhaging that results from mechanical damage during SCI as well as the secondary phase lesion that lasts several hours or even several months and is accompanied by edema, hemorrhage, inflammation, and cytotoxic edema [44,45,46,47] and may extend to the white matter area and lead to white matter degeneration and damage [48, 49]

But remember the 28-day stability rule: once reconstituted, the solution should be used within 28 days

Scalp inflammation reduction begins within 24 weeks