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Cytoskeletal & Cell Migration Pathways The peptide influences actin cytoskeleton dynamics through the FAK (Focal Adhesion Kinase) / Paxillin signaling axis

Carmel R, Tatsis B, Baril L

In combination with the EGFR inhibitor gefitinib, crizotinib showed greater inhibition of cell survival in vitro as well as impaired wound closure and invasion