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Fsp1 knockout enhanced CaOX-induced ferroptosis in MTECs To further investigate the role of Fsp1 in oxalate-induced AKI, the CRISPR-Cas9 system was employed to create Fsp1 knockout MTECs and confirmed through Sanger sequencing and Western blot analysis (Fig

mix in 200 ml of 5% dextrose and infused in one hour 50mg/kg in 500 ml of 5% dextrose over 4 hours 100mg/kg in 1000 ml of 5% dextrose over 16 hours