In a recent review (2018) by the famous Cochrane Institute, it was reported that studies which had been published on this topic only provided very low-quality evidence that oral B12 is as efficacious as intramuscular B12
no IGF1 increase
However, the overall results depend on the consistency of treatment and maintaining healthy lifestyle habits
Frequently Asked Questions References [1] [2] National Library of Medicine, Gastric pentadecapeptide body protection compound BPC 157 and its role in accelerating musculoskeletal soft tissue healing, Gwyer, D., Wragg, N., Wilson, S., 2017 [3] [5] National Library of Medicine, Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review, Vasireddi, N., Hahamyan, H., Salata, M., Karns, M., Calcei, J., Voos, J., Apostolakos, J., July 2025 [4] National Library of Medicine, Modulatory effects of BPC 157 on vasomotor tone and the activation of Src-Caveolin-1-endothelial nitric oxide synthase pathway, Hsieh, M., Lee, C., Cheh, H., Chang, G, Huang, H., Lin, Y., Pang, J., October, 2020
