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PMID 11935176

doi:10.7150/ijms.106360 This issue Cite Research Paper 1

This rapid clearance may help prevent the toxic accumulation of mediators in the bloodstream, significantly reducing the severity and duration of systemic MCAS flares, such as flushing, gastrointestinal distress, and neurological inflammation

Premature puberty Pregnancy or suspicion of pregnancy Breast feeding Blood clotting disorders (HCG can potentially increase the risk of blood clots, which can be dangerous in these patients)