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Guo Q, Wang Y, Xu D, et al

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Preclinical studies lasting up to 6 weeks showed no adverse effects across liver, spleen, lung, kidney, brain, thymus, prostate, and ovary tissues

Tanaka K, Sasayama T, Irino Y, Takata K, Nagashima H, Satoh N, Kyotani K, Mizowaki T, Imahori T, Ejima Y, Masui K, Gini B, Yang H, Hosoda K, Sasaki R, Mischel PS, Kohmura E (2015) Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment